MUCOADHESIVE BUCCAL PATCHES OF LORNOXICAM: II– IN-VIVO EVALUATION AND CLINICAL EFFICACY
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چکیده
منابع مشابه
Formulation and In-vitro Evaluation of Mucoadhesive Buccal Patches of Cyproheptadine Hydrochloride
The goal of the present investigation was to design and evaluate mucoadhesive buccal patches of Cyproheptadine Hydrochloride (CPH) which is a sedating antihistamine with antimuscarinic, serotonin-antagonist, and calcium-channel blocking action. Buccal films were made with Hydroxy propylcellulose (HPC EF) and Hydroxy Propyl Methyl Cellulose (HPMC E15) as mucoadhesive polymers. Permeation of CPH ...
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Purpose: To develop mucoadhesive patches for buccal administration of metoprolol succinate and to evaluate their in vitro and in vivo bioadhesion. Methods: The mucoadhesive buccal patches were prepared by solvent casting technique using two different mucoadhesive polymers. The formulations were tested for in vitro drug permeation studies, buccal absorption, in vitro drug release studies, moistu...
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The purpose of the study was to develop Tizanidine HCl (TZN) and Meloxicam (MLX) loaded bilayer mucoadhesive films intended for buccal administration, aiming to enhance the bioavailability. Bilayer films were prepared by solvent evaporation technique selecting arabinoxylan (ARX) as a sustained release (SR) layer forming polymer and hydroxypropyl methylcellulose (HPMC) E-15 as an immediate relea...
متن کاملIn-vitro and In-vivo Evaluation of Novel Mucoadhesive Buccal Drug Delivery Systems-a Review
The buccal mucosa is one of the administration sites that might provide an alternative for peroral administration. Mucoadhesive buccal drug delivery systems is one of the most important novel drug delivery systems with its various advantages and it has a lot of potential in formulating dosage forms for various chronic diseases. The delivery of drugs through the buccal mucosa has attracted much ...
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ژورنال
عنوان ژورنال: Bulletin of Pharmaceutical Sciences. Assiut
سال: 2011
ISSN: 1110-0052
DOI: 10.21608/bfsa.2011.63214